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Choline alfoscerate (GPC) 28319-77-9
Product Specification
| Appearance: | Fine power with highly hygroscopic |
| Color: | White to light yellow |
| Odor: | Neutral |
| Identification: | Positive |
| Bulk density (g/cc): | 0.9-1.08 |
| Specification rotation [a]25D: | -2.4 to -2.95 |
| Solubility (H2O,10%W/W): | Clear |
| Color of solution : | NMT Y7 |
| Loss on drying : | 2.0% Max |
| PH : | 5.0~7.0 |
| Heavy metals: | NMT 10ppm |
| Arsenic (As2O3): | NMT 1ppm |
| Sulfate (SO4): | NMT 0.02% |
| Iron (Fe): | NMT 10ppm |
| Chloride (Cl): | NMT 0.02% |
| Solvent residual: | Meeting USP standard |
| G.P.E.: | NMT 0.2% |
| Glycerophosric acid: | NMT 0.2% |
| Assay NLT: | 99.00% |
description1
PRODUCT DESCRIPTION
Choline alfoscerate is a nootropic reportedly effective in the treatment of age-associated memory impairment. In man, it decreased and prevented scopolamine-induced amnesia. In vitro studies suggest that choline alfoscerate acts indirectly on cholinergic transmission by elevating the synthesis of acetylcholine.
Choline glycerophosphate (GPC) is a white waxy solid that is miscible with water, soluble in methanol and ethanol, and insoluble in chloroform, ether, oil, etc. It has no characteristic absorption under UV visible light. The methods for determining GPC content include high-performance liquid chromatography (equipped with an evaporative light scattering detector or refractive index differential detector) and the digestion phosphorus determination method.
sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a phospholipid; precursor in choline biosynthesis. sn-Glycero-3-phosphocholine is an intermediate in catabolic pathway of phosphatidylcholine. sn-Glycero-3-phosphocholine is used as an Nootropic.
Choline alfoscerate is a member of the class of phosphocholines that is the choline ester of sn-glycero-3-phosphate. It is one of the major osmolyte in the renal medullary cells. It has a role as a parasympatholytic, a neuroprotective agent, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a member of sn-glycerol 3-phosphates and a member of phosphocholines.