Docusate 577-11-7 Treating constipation / Gastrointestinal medication

Sodium docetate is a chemical substance. Sodium Doctorate is an anionic surfactant. This drug is a non irritating laxative that can reduce the surface tension of intestinal fluids. After oral administration, it can allow water and fat substances to penetrate feces in the intestine, promoting their softening. Generally, it takes 1-2 days to take effect. The drug is mainly excreted through bile. Doctorate sodium acts in the gastrointestinal tract. There is evidence to suggest that sodium docetate is absorbed and excreted through bile, and there is also evidence to suggest that sodium docetate can enhance the absorption of certain medications taken simultaneously.

Chronic functional constipation is a common gastrointestinal disease in clinical practice, characterized by infrequent bowel movements, incomplete bowel movements, difficulty in defecation, and hard and dry stools. The onset of chronic functional constipation is related to various factors such as age, diet, environment, and physiological rhythm, which have a serious impact on human health and are also triggering factors for various serious gastrointestinal diseases. Guidelines such as the "Expert Consensus on Integrated Traditional Chinese and Western Medicine Diagnosis and Treatment of Functional Constipation in the Elderly" (2019), the "Expert Consensus on Evaluation and Management of Chronic Constipation in the Elderly" (2017), the American Gastroenterological Association (AGA) Constipation Diagnosis and Treatment Guidelines (2013), and the World Gastrointestinal Organization (WGO) Constipation: Global Perspectives (2010) all recommend the use of excessive sodium citrate as an effective medication for treating constipation. Sodium docetate has a mild effect and excellent therapeutic efficacy. Doctorate sodium tablets are available in both the European Union and the United States. Approved for use in adults and children abroad, it is a safe and effective medication for treating constipation.

The ingredient of this drug, sodium octyl sulfonate (DSS), can also be used as a food additive, emulsifier, dispersant, and wetting agent.