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L-Carnosine 305-84-0 antioxidant and anti glycation

IUPAC Name: (2S)-2-(3-aminopropanoylamino)-3-(1H-imidazol-5-yl)propanoic acid  
Molecular Weight:226.24
Molecular Formula:C9H14N4O3
Quality Standard:In House

    Product Specification

    Appearance:

    White powder

    Melting point:

    253 ° C (dec.) (lit.)

    Specific rotation:

    20.9 º (c=1.5, H2O)

    Boiling point:

    367.84 ° C (rounding temperature)

    Density:

    1.2673 (roughness)

    Vapor pressure:

    0Paat25 ℃

    Refractive index:

    21 ° (C=2, H2O)

    Storage conditions:

    -20 ° C

    Solubility:

    soluble in DMSO (very mild), water (mild)

    Acidity coefficient (pKa):

    2.62 (at 25 ℃)

    description1

    PRODUCT DESCRIPTION

    Carnosine, scientific name β - alanyl-L-histidine, is a dipeptide composed of two amino acids, β - alanine and L-histidine, in a crystalline solid form. The tissues of muscles and brain contain high concentrations of myopeptides. Carnosine was discovered by Russian chemist Gulevich along with carnitine. Studies in the UK, South Korea, Russia, and other countries have shown that creatine has strong antioxidant capacity and is beneficial to the human body. Carnosine has been proven to clear reactive oxygen species (ROS) and alpha - β unsaturated aldehydes formed by excessive oxidation of fatty acids on the cell membrane during oxidative stress.

    In animal experiments, supplementing with creatine can increase the content of corticosteroids, which may explain the hyperactivity symptoms sometimes caused by the use of high doses of creatine. However, the above study injected creatine into the ventricles of chickens, and the phenomenon of increased corticosteroids content has not yet been observed in human experiments. In animal experiments, it has been found that myopeptides can slow down the growth of cancer cells, prevent oxidative stress caused by alcohol and chronic liver damage caused by ethanol. In mouse experiments, the neuroprotective mechanism of myopeptides can prevent permanent brain ischemia.

    International research has confirmed that myopeptides have good anti glycation effects. Carbonylated proteins and glycation end products (AGEs) are signals of cellular aging. They accumulate abnormally inside cells, accelerating cross-linking with other proteins. Carnosine can replace proteins in the body by reacting with sugar before it erodes the skin, thereby helping to protect proteins from glycation and achieving anti glycation effects.

    Carnosine is not only a nutrient, but also promotes cellular metabolism and delays aging. Carnosine can capture free radicals, prevent glycation reactions, and has antioxidant and anti glycation effects. It can be used in combination with whitening ingredients to enhance its whitening effect.